(1) Small GTP-binding protein which seems to antagonise ras activity. Has antimitogenic activity, seems to be involved in NGF-induced neuronal differentiation and T-cell activation. Activated by CRK adaptor proteins and rap-specific GEFs. See tuberous sclerosis. (2) Rhoptry-associated protein 1 of Plasmodium falciparum , a potential component of an anti-malarial vaccine.
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